Chemometric QSAR Modeling and In Silico Design of Antioxidant NO Donor Phenols
نویسندگان
چکیده
منابع مشابه
Chemometric QSAR Modeling and In Silico Design of Antioxidant NO Donor Phenols
An acceleration of free radical formation within human system exacerbates the incidence of several life-threatening diseases. The systemic antioxidants often fall short for neutralizing the free radicals thereby demanding external antioxidant supplementation. Therein arises the need for development of new antioxidants with improved potency. In order to search for efficient antioxidant molecules...
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The quantitative structure activity relationship paradigm provides an excellent avenue for investigating ligand–receptor interactions in medicinal chemistry/toxicology. Lateral validation of models formulated using this approach allows for a cohesive understanding of the mechanistic underpinnings of a specific class of related molecules. The diverse biological activities of substituted phenols ...
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There are very few studies for combinatorial library design and high throughput screening of 4-anilinoquinoline antimalarial compounds having activities against parasitic strain of P. falciparum. Therefore, an attempt has been made in the present paper to design potent lead compounds in this congener utilizing quantitative structure activity relationship utilizing theoretical molecular descript...
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چکیده بررسی فعالیت ضد اکسیدانی و ضدمیکروبی عصاره گیاه بن سرخ (allium jesdianum) به کوشش: زهرا مقیمی هدف از این تحقیق بررسی میزان ترکیبات فنولی کل، ترکیبات فلاوونوئیدی کل، فعالیت ضداکسیدانی و ضدمیکروبی عصاره ی گیاه تازه و خشک بن سرخ بود. استخراج عصاره به روش های غوطه وری، استفاده از همزن مغناطیسی، دستگاه مایکروویو، امواج فراصوت و گرمادهی مقاومتی و با استفاده از متانول، اتانول و آب به عنوا...
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ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2011
ISSN: 0036-8709,2218-0532
DOI: 10.3797/scipharm.1011-02